VEGFR2/CD309 antibody (pTyr951)

Catalog No. ABIN218845

This Rabbit Polyclonal antibody specifically detects VEGFR2/CD309 in WB and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for VEGFR2/CD309 antibody (pTyr951) (ABIN218845)

Target: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VEGFR2/CD309 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-VEGFR2/CD309 Antibody

Binding Specificity: pTyr951

Specificity: Detects overexpressed human VEGFR-2 only when phosphorylated at tyrosine 951. Does not cross-react with other phosphorylated receptor tyrosine kinases. Species cross-reactivity: Predicted to cross-react with mouse based on 100 % sequence homology.

Purification: Immunoaffinity purified

Immunogen: Synthetic phospho-peptide (KLH coupled) corresponding to residues surrounding Tyr951 of human VEGF receptor 2.

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: IP (1:50), WB (1:1000)

Usage: Suitable for use in Western Blot and Immunoprecipitation. Western Blot: 1:1000, incubate membrane with diluted antibody in 5 % BSA, 1X TBS, 0.1 % Tween-20 at 4?C with gentle shaking, overnight. Immunoprecipitation: 1:50.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol. No preservative added.

Preservative: Without preservative

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for VEGFR2/CD309

Target: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Alternative Name: KDR / VEGFR2

Background: Name/Gene ID: KDR
Subfamily: VEGF Receptor
Family: Protein Kinase

Synonyms: KDR, CD309, Fetal liver kinase 1, Fetal liver kinase-1, FLK-1, FLK1, Kinase insert domain receptor, Quek1, VEGFR, VEGFR2, Soluble VEGFR2, VEGF receptor 2, VEGFR-2, CD309 antigen, VEGF-R2

Gene ID: 3791

UniProt: P35968

Pathways: RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling